| Date | Location | Result | |
| 03/05/11 | Bethlehem, Pa. (Stabler Arena) | Lehigh 82, Lafayette 58 | Box score |
| 02/26/11 | Washington, D.C. (Bender Arena) | American 82, Lafayette 47 | Box score |
| 02/23/11 | Christl Arena (West Point, N.Y.) | Army 58, Lafayette 36 | Box score |
| 02/19/11 | Easton, Pa. (Kirby Sports Center) | Lehigh 70, Lafayette 49 | Box score |
| 02/16/11 | Lewisburg, Pa. (Sojka Pavilion) | Bucknell 46, Lafayette 34 | Box score |
| 02/12/11 | Easton, Pa. (Kirby Sports Center) | Lafayette 58, Navy 53 | Box score |
| 02/09/11 | Easton, Pa. (Kirby Sports Center) | Lafayette 65, Colgate 42 | Box score |
| 02/05/11 | Worcester, Mass. (Hart Center) | Holy Cross 83, Lafayette 46 | Box score |
| 01/29/11 | Easton, Pa. (Kirby Sports Center) | American 66, Lafayette 51 | Box score |
| 01/26/11 | Easton, Pa. (Kirby Sports Center) | Lafayette 54, Army 42 | Box score |
| 01/22/11 | Bethlehem, Pa. (Stabler Arena) | Lafayette 57, Lehigh 54 | Box score |
| 01/19/11 | Easton, Pa. (Kirby Sports Center) | Bucknell 57, Lafayette 49 | Box score |
| 01/15/11 | Annapolis, Md. (Alumni Hall) | Navy 61, Lafayette 52 | Box score |
| 01/12/11 | Hamilton, N.Y. (Cotterell Court) | Colgate 64, Lafayette 60 | Box score |
| 01/08/11 | Easton, Pa. (Kirby Sports Center) | Holy Cross 72, Lafayette 67 | Box score |
| 01/05/11 | New York, N.Y. (Levien Gymnasium) | Lafayette 64, Columbia 63 | Box score |
| 01/02/11 | Easton, Pa. (Kirby Sports Center) | Penn 59, Lafayette 52 | Box score |
| 12/29/10 | Philadelphia, Pa. (Hagan Arena) | St. Joseph's 75, Lafayette 40 | Box score |
| 12/28/10 | Philadelphia, Pa. (Hagan Arena) | Lafayette 56, Quinnipiac 54 | Box score |
| 12/13/10 | Princeton, N.J. (Jadwin Gymnasium) | Princeton 90, Lafayette 58 | Box score |
| 12/11/10 | Easton, Pa. (Kirby Sports Center) | Lafayette 60, La Salle 51 | Box score |
| 12/09/10 | Riverdale, N.Y. (Draddy Gymnasium) | Lafayette 53, Manhattan 50 | Box score |
| 12/04/10 | Easton, Pa. (Kirby Sports Center) | Lafayette 51, Fairleigh Dickinson 37 | Box score |
| 12/01/10 | St. Bonaventure, N.Y. (Reilly Center) | St. Bonaventure 72, Lafayette 63 | Box score |
| 11/28/10 | Easton, Pa. (Kirby Sports Center) | Fairfield 52, Lafayette 39 | Box score |
| 11/26/10 | West Long Branch, N.J. (The MAC) | Monmouth 68, Lafayette 54 | Box score |
| 11/23/10 | Easton, Pa. (Kirby Sports Center) | Lafayette 74, St. Francis (N.Y.) 52 | Box score |
| 11/20/10 | Lynchburg, Va. (Vines Center) | Liberty 64, Lafayette 52 | Box score |
| 11/17/10 | Brooklyn, N.Y. (Wellness Center) | Long Island 64, Lafayette 59 | Box score |
| 11/14/10 | Easton, Pa (Kirby Sports Center) | Lafayette 84, Bryant 80 | Box score |
