| Date | Opponent / Event | Location | Time / Result | Media | |
|
| 11/09/07 | vs. Wagner | Easton, Pa. | L, 74-70 | Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 11/12/07 | at Stony Brook | Stony Brook, N.Y. | W, 76-68 (OT) | Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 11/16/07 | vs. Fairleigh Dickinson | Easton, Pa. | L, 98-92 | Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 11/20/07 | vs. UMBC | Easton, Pa. | W, 87-84 (OT) | TV: Lafayette Sports Network (RCN, WBPH) | More |
| 11/25/07 | vs. CCSU | Easton, Pa. | W, 71-54 | TV: Lafayette Sports Network (RCN, WBPH) Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 11/28/07 | vs. Penn | Easton, Pa. | W, 81-69 | TV: Lafayette Sports Network (RCN, WBPH) Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 12/03/07 | vs. NJIT | Easton, Pa. | W, 81-56 | Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 12/05/07 | at Rutgers | New Brunswick, N.J. | L, 90-79 | TV: Lafayette Sports Network (RCN, WBPH, SportsNet NY) Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 12/08/07 | at Columbia | New York, N.Y. | W, 78-64 | Radio: Lafayette Sports Network (WGPA-AM 1100) | More |
| 12/19/07 | at Towson | Towson, Md. | W, 79-69 (OT) | | More |
| 12/21/07 | at Mount St. Mary's | Emmitsburg, Md. | W, 76-72 | | More |
| 12/30/07 | at Robert Morris | Moon Township, Pa. | L, 88-76 | Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 01/02/08 | at Pittsburgh | Pittsburgh, Pa. | L, 96-75 | TV: ESPNU Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 01/05/08 | at Mississippi State | Jackson, Miss. | L, 77-53 | Radio: Lafayette Sports Network (WGPA-AM 1100) | More |
| 01/09/08 | at Princeton | Princeton, N.J. | W, 76-71 (OT) | TV: Lafayette Sports Network (RCN, WBPH, FSNP) | More |
| 01/12/08 | vs. Holy Cross * | Easton, Pa. | W, 60-52 | TV: Lafayette Sports Network (RCN, WBPH, FSNP) Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 01/16/08 | at Colgate * | Hamilton, N.Y. | W, 69-68 (OT) | Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 01/19/08 | at Navy * | Annapolis, Md. | W, 103-99 (OT) | Radio: Lafayette Sports Network (WGPA-AM 1100) | More |
| 01/23/08 | vs. Bucknell | Easton, Pa. | W, 80-68 | TV: Lafayette Sports Network (RCN, WBPH, FSNP) | More |
| 01/26/08 | at Lehigh | Bethlehem, Pa. | L, 60-55 | Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 01/30/08 | vs. Army * | Easton, Pa. | W, 83-58 | TV: Lafayette Sports Network (RCN, WBPH, FSNP) Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 02/02/08 | vs. American * | Easton, Pa. | L, 87-76 | TV: Lafayette Sports Network (RCN, WBPH, MASN) Radio: Lafayette Sports Network (WGPA-AM 1100) | More |
| 02/09/08 | at Holy Cross * | Worcester, Mass | L, 77-57 | Radio: Lafayette Sports Network (WGPA-AM 1100) | More |
| 02/13/08 | vs. Colgate * | Easton, Pa. | L, 76-75 | TV: Lafayette Sports Network (RCN, WBPH, FSNP) Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 02/16/08 | vs. Navy * | Easton, Pa. | L, 82-80 | TV: Lafayette Sports Network (RCN, WBPH, CSTV) Radio: Lafayette Sports Network (WGPA-AM 1100) | More |
| 02/20/08 | at Bucknell * | Lewisburg, Pa. | L, 77-75 (OT) | Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 02/23/08 | vs. Lehigh * | Easton, Pa. | W, 78-60 | TV: Lafayette Sports Network (RCN, WBPH, CSTV) Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 02/27/08 | at Army * | West Point, N.Y. | L, 65-60 | Radio: Lafayette Sports Network (WSAN-AM 1470) | More |
| 03/01/08 | at American * | Washington, D.C. | L, 84-72 | Radio: Lafayette Sports Network (WGPA-AM 1100) | More |
| 03/05/08 | at Colgate (Patriot League Quarterfinals) | Hamilton, N.Y. | L, 76-74 | | More |
