| Date | Location | Result | |
| Nov 13, 2010 | Easton, Pa. | American 3, Lafayette 0 (25-14,25-23,25-9) | Box score |
| Nov 12, 2010 | Easton, Pa. | Lafayette 3, Navy 2 (22-25,25-18,15-25,25-23,15-12) | Box score |
| Nov 06, 2010 | Lewisburg, Pa. | Bucknell 3, Lafayette 0 (25-22,25-19,25-14) | Box score |
| Nov 05, 2010 | Hamilton, N.Y. | Colgate 3, Lafayette 0 (25-9,25-15,25-16) | Box score |
| Oct 29, 2010 | Bethlehem, Pa. | Lehigh 3, Lafayette 0 (25-14,25-17,25-13) | Box score |
| Oct 23, 2010 | Easton, Pa. | Holy Cross 3, Lafayette 1 (20-25,25-22,31-29,25-16) | Box score |
| Oct 22, 2010 | Easton, Pa. | Army 3, Lafayette 0 (25-6,25-17,25-14) | Box score |
| Oct 16, 2010 | Annapolis, Md. | Navy 3, Lafayette 2 (25-21,28-30,16-25,25-23,15-11) | Box score |
| Oct 15, 2010 | Washington, D.C. | AMERICAN 3, Lafayette 0 (25-8,25-15,25-10) | Box score |
| Oct 07, 2010 | Easton, Pa. | Lehigh 3, Lafayette 1 (23-25,25-19,25-13,25-14) | Box score |
| Oct 05, 2010 | Easton, Pa. | NJIT 3, Lafayette 1 (25-10,25-27,25-15,25-23) | Box score |
| Oct 02, 2010 | Easton, Pa. | Colgate 3, Lafayette 0 (25-18,25-22,27-25) | Box score |
| Oct 01, 2010 | Easton, Pa. | Bucknell 3, Lafayette 0 (25-14,25-15,33-31) | Box score |
| Sep 25, 2010 | West Point, N.Y. | Army 3, Lafayette 0 (25-22,25-21,25-10) | Box score |
| Sep 24, 2010 | Worcester, Mass. | Holy Cross 3, Lafayette 0 (25-15,25-21,25-19) | Box score |
| Sep 22, 2010 | Riverdale, N.Y. | Manhattan 3, Lafayette 0 (25-13,25-21,25-22) | Box score |
| Sep 18, 2010 | Easton, Pa. | Delaware State 3, Lafayette 1 (21-25,25-12,25-17,25-23) | Box score |
| Sep 18, 2010 | Easton, Pa. | Quinnipiac 3, Lafayette 0 (25-21,25-16,25-10) | Box score |
| Sep 17, 2010 | Easton, Pa. | Lafayette 3, La Salle 1 (25-22,15-25,25-17,25-21) | Box score |
| Sep 11, 2010 | New York, N.Y. | CCSU 3, Lafayette 1 (19-25,25-14,25-10,25-14) | Box score |
| Sep 11, 2010 | New York, N.Y. | IONA 3, Lafayette 0 (25-19,25-8,25-23) | Box score |
| Sep 10, 2010 | New York, N.Y. | Columbia 3, Lafayette 0 (25-11,25-17,25-17) | Box score |
| Sep 08, 2010 | Easton, Pa. | Lafayette 3, Coppin State 1 (24-26,25-21,25-18,25-16) | Box score |
| Sep 04, 2010 | Easton, Pa. | Lafayette 3, St. Peter's 2 (25-16,21-25,25-13,21-25,15-11) | Box score |
| Sep 04, 2010 | Easton, Pa. | Lafayette 3, Fairleigh Dickinson 0 (25-22,25-20,25-16) | Box score |
| Sep 03, 2010 | Easton, Pa. | Princeton 3, Lafayette 0 (25-14,25-17,25-16) | Box score |
| Sep 01, 2010 | Washington, D.C. | Howard 3, Lafayette 1 (17-25,25-21,25-17,25-8) | Box score |
| Aug 30, 2010 | Easton, Pa. | St. Francis (N.Y.) 3, Lafayette 1 (22-25,25-21,25-23,25-19) | Box score |
